Single-cell Bayesian deconvolution

Summary: Individual cells exhibit substantial heterogeneity in protein abundance and activity, which is frequently reflected in broad distributions of fluorescently labeled reporters. Since all cellular components are intrinsically fluorescent to some extent, the observed distributions contain backg...

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Bibliographic Details
Main Authors: Gabriel Torregrosa-Cortés, David Oriola, Vikas Trivedi, Jordi Garcia-Ojalvo
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223020187