dTrmt10A impacts Hsp70 chaperone m6A levels and the stress response in the Drosophila brain

Abstract Chronic cellular stress has a profound impact on the brain, leading to degeneration and accelerated aging. Recent work has revealed the vital role of RNA modifications, and the proteins responsible for regulating them, in the stress response. In our study, we defined the role of CG14618/dTr...

Full description

Bibliographic Details
Main Authors: Alexandra E. Perlegos, Xiuming Quan, Kirby M. Donnelly, Hui Shen, Emily J. Shields, Heidi Elashal, Kathy Fange Liu, Nancy M. Bonini
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-50272-4