How Estrogen, Testosterone, and Sex Differences Influence Serum Immunoglobulin Isotype Patterns in Mice and Humans

Females often exhibit superior immune responses compared to males toward vaccines and pathogens such as influenza viruses and SARS-CoV-2. To help explain these differences, we first studied serum immunoglobulin isotype patterns in C57BL/6 male and female mice. We focused on IgG2b, an isotype that le...

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Bibliographic Details
Main Authors: Sherri L. Surman, Bart G. Jones, Rhiannon R. Penkert, Robert E. Sealy, Tony Marion, Paul G. Thomas, Geoffrey Neale, Beisi Xu, Julia L. Hurwitz
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/15/2/482