Time-dependent phenotypical changes of microglia drive alterations in hippocampal synaptic transmission in acute slices

Time-dependent phenotypical changes of microglia drive alterations in hippocampal synaptic transmission in acute slices

It is widely acknowledged that microglia actively regulate synaptic function in the brain. Remarkably, much of our understanding regarding the role of microglia in synaptic regulation is derived from studies in acute brain slices. However, it is still uncertain to what extent the preparation and mai...

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Bibliographic Details
Main Authors: Laura Ferrucci, Bernadette Basilico, Ingrid Reverte, Francesca Pagani, Giorgia Scaringi, Federica Cordella, Barbara Cortese, Gaia De Propris, Andrea Galeone, Letizia Mazzarella, Alessandro Mormino, Stefano Garofalo, Azka Khan, Valeria De Turris, Valentina Ferretti, Paola Bezzi, Cornelius Gross, Daniele Caprioli, Cristina Limatola, Silvia Di Angelantonio, Davide Ragozzino
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
microglia
acute slices
synaptic transmission
microglia reactivity
electrophysiology
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2024.1456974/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2024.1456974/full

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