miR-101 Promotes Breast Cancer Cell Apoptosis by Targeting Janus Kinase 2

Aims: microRNA-101 (miR-101) is down-regulated in several cancers. In this study, we explored the effects of dysregulated miR-101 on breast cancer cells and the underlying mechanisms. Methods: miR-101 level was quantified by real-time RT-PCR. Cell viability was analyzed by MTT assay. Apoptosis was d...

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Bibliographic Details
Main Authors: Lu Wang, Linqiang Li, Rui Guo, Xuelian Li, Ying Lu, Xiaoxiang Guan, Samuel Chege Gitau, Leimin Wang, Chaoqian Xu, Baofeng Yang, Hongli Shan
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Online Access:http://www.karger.com/Article/FullText/363010