Differential regional distribution of phosphorylated tau and synapse loss in the nucleus accumbens in tauopathy model mice

Differential regional distribution of phosphorylated tau and synapse loss in the nucleus accumbens in tauopathy model mice

Tauopathies differ in terms of the brain regions that are affected. In Alzheimer's disease, basal forebrain and hippocampus are mainly involved, while frontotemporal lobar degeneration affects the frontal and temporal lobes and subcortical nuclei including striatum. Over 90% of human cases of t...

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Bibliographic Details
Main Authors: Taiki Kambe, Yumiko Motoi, Ran Inoue, Nobuhiko Kojima, Norihiro Tada, Tetsuya Kimura, Naruhiko Sahara, Shunji Yamashita, Tatsuya Mizoroki, Akihiko Takashima, Kohei Shimada, Koichi Ishiguro, Hiroshi Mizuma, Hirotaka Onoe, Yoshikuni Mizuno, Nobutaka Hattori
Format: Article
Language:English
Published: Elsevier 2011-06-01
Series:Neurobiology of Disease
Subjects:
Tauopathy
Synapse
Nucleus accumbens
Phosphorylated tau
Anxiety
Wild-type tau
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996111000568

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http://www.sciencedirect.com/science/article/pii/S0969996111000568

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