Experimenter familiarization is a crucial prerequisite for assessing behavioral outcomes and reduces stress in mice not only under chronic pain conditions

Abstract Rodent behavior is affected by different environmental conditions. These do not only comprise experimental and housing conditions but also familiarization with the experimenter. However, specific effects on pain-related behavior and chronic pain conditions have not been examined. Therefore,...

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Bibliographic Details
Main Authors: Daniel Segelcke, Steven R. Talbot, Rupert Palme, Carmen La Porta, Esther Pogatzki-Zahn, André Bleich, Anke Tappe-Theodor
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-29052-7