Multi-omics profiles refine L-dopa decarboxylase (DDC) as a reliable biomarker for prognosis and immune microenvironment of clear cell renal cell carcinoma

Multi-omics profiles refine L-dopa decarboxylase (DDC) as a reliable biomarker for prognosis and immune microenvironment of clear cell renal cell carcinoma

BackgroundIncreasing evidence indicates that L-dopa decarboxylase (DDC), which mediates aberrant amino acid metabolism, is significantly associated with tumor progression. However, the impacts of DDC are not elucidated clearly in clear cell renal cell carcinoma (ccRCC). This study aimed to evaluate...

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Bibliographic Details
Main Authors: Kun Chang, Jiaqi Su, Chuanyu Li, Aihetaimujiang Anwaier, Wangrui Liu, Wenhao Xu, Yuanyuan Qu, Hailiang Zhang, Dingwei Ye
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Oncology
Subjects:
l-DOPA decarboxylase
amino acids metabolism
tumor microenvironment
clear cell renal cell carcinoma (ccRCC)
prognosis
biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1079446/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.1079446/full

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