Effects of Blocking NLRP3 Inflammasome on Type II Innate Lymphoid Cell Response in Allergic Rhinitis

Effects of Blocking NLRP3 Inflammasome on Type II Innate Lymphoid Cell Response in Allergic Rhinitis

Background: Type 2 innate lymphoid cells (ILC2s) and NLRP3 inflammasome are related to allergic and inflammatory responses. NLRP3 inflammasome inhibitor MCC950 was demonstrated to ameliorate allergic rhinitis (AR) in animal models.Objective: To elucidate the effect of MCC950 on ILC2 responses in AR....

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Bibliographic Details
Main Authors: Guoqing Gong, Peng Huang, Changliang Yang, Chengcheng Huang, Zhao Zhang, Ruiyao Chen, Tingfeng Sun, Guang Yang
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2023-09-01
Series:Iranian Journal of Immunology
Subjects:
allergic rhinitis
mcc950
nlrp3 inflammasome
type ii innate lymphoid cell
Online Access:https://iji.sums.ac.ir/article_49485_5cae5ae3716dfad7466bdfa7afcdf250.pdf

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https://iji.sums.ac.ir/article_49485_5cae5ae3716dfad7466bdfa7afcdf250.pdf

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