Molecular Mechanisms of Alcohol-Induced Colorectal Carcinogenesis

Molecular Mechanisms of Alcohol-Induced Colorectal Carcinogenesis

The etiology of colorectal cancer (CRC) is complex. Approximately, 10% of individuals with CRC have predisposing germline mutations that lead to familial cancer syndromes, whereas most CRC patients have sporadic cancer resulting from a combination of environmental and genetic risk factors. It has be...

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Bibliographic Details
Main Authors: Caroline H. Johnson, Jaya Prakash Golla, Evangelos Dioletis, Surendra Singh, Momoko Ishii, Georgia Charkoftaki, David C. Thompson, Vasilis Vasiliou
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
CRC
carcinogenesis
alcohol
acetaldehyde
ALDH1B1
CYP2E1
Online Access:https://www.mdpi.com/2072-6694/13/17/4404

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https://www.mdpi.com/2072-6694/13/17/4404

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