Loss of Response to Long-Term Infliximab Therapy in Children with Crohn’s Disease
Secondary loss of response (LoR) often precludes further use of infliximab in children with Crohn’s disease. Immunomodulators may reduce the incidence of LoR but their combination with infliximab presents safety concerns. We aimed to determine the long-term durability of infliximab response in paedi...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2013-10-01
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Series: | Pharmaceuticals |
Subjects: | |
Online Access: | http://www.mdpi.com/1424-8247/6/10/1322 |