Transcriptomic analysis reveals novel mechanistic insight into murine biological responses to multi-walled carbon nanotubes in lungs and cultured lung epithelial cells.

Transcriptomic analysis reveals novel mechanistic insight into murine biological responses to multi-walled carbon nanotubes in lungs and cultured lung epithelial cells.

There is great interest in substituting animal work with in vitro experimentation in human health risk assessment; however, there are only few comparisons of in vitro and in vivo biological responses to engineered nanomaterials. We used high-content genomics tools to compare in vivo pulmonary respon...

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Bibliographic Details
Main Authors: Sarah Søs Poulsen, Nicklas R Jacobsen, Sarah Labib, Dongmei Wu, Mainul Husain, Andrew Williams, Jesper P Bøgelund, Ole Andersen, Carsten Købler, Kristian Mølhave, Zdenka O Kyjovska, Anne T Saber, Håkan Wallin, Carole L Yauk, Ulla Vogel, Sabina Halappanavar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3834097?pdf=render

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http://europepmc.org/articles/PMC3834097?pdf=render

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