Optogenetic engineered umbilical cord MSC-derived exosomes for remodeling of the immune microenvironment in diabetic wounds and the promotion of tissue repair

Optogenetic engineered umbilical cord MSC-derived exosomes for remodeling of the immune microenvironment in diabetic wounds and the promotion of tissue repair

Abstract Background Angiogenesis and tissue repair in chronic non-healing diabetic wounds remain critical clinical problems. Engineered MSC-derived exosomes have significant potential for the promotion of wound healing. Here, we discuss the effects and mechanisms of eNOS-rich umbilical cord MSC exos...

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Bibliographic Details
Main Authors: Xin Zhao, Luoqin Fu, Hai Zou, Yichen He, Yi Pan, Luyi Ye, Yilin Huang, Weijiao Fan, Jungang Zhang, Yingyu Ma, Jinyang Chen, Mingang Zhu, Chengwu Zhang, Yu Cai, Xiaozhou Mou
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Journal of Nanobiotechnology
Subjects:
Engineering stem cell-derived exosomes
Diabetic chronic wounds
Angiogenesis
Optogenetics
Immune microenvironment
Online Access:https://doi.org/10.1186/s12951-023-01886-3

Internet

https://doi.org/10.1186/s12951-023-01886-3

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