Profound Inhibitory and Apoptotic Effects of Histone Deacetylase Inhibitor Valproic Acid on Different Cancers

Objectives: Histone acetylation is determined by a balance between the activities of the enzymes that are involved in the histone modifications, including histone deacetylases (HDACs) and histone acetyltransferases which affect gene expression and play a significant role in carcinogens. Valproic aci...

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Bibliographic Details
Main Authors: Masumeh Sanaei, Fraidoon Kavoosi
Format: Article
Language:English
Published: Aras Part Medical International Press 2019-10-01
Series:Crescent Journal of Medical and Biological Sciences
Subjects:
Online Access:http://www.cjmb.org/pdf.php?id=284