Microfluidic/HPLC combination to study carnosine protective activity on challenged human microglia: Focus on oxidative stress and energy metabolism

Microfluidic/HPLC combination to study carnosine protective activity on challenged human microglia: Focus on oxidative stress and energy metabolism

Carnosine (β-alanyl-L-histidine) is a naturally occurring endogenous peptide widely distributed in excitable tissues such as the brain. This dipeptide possesses well-demonstrated antioxidant, anti-inflammatory, and anti-aggregation properties, and it may be useful for treatment of pathologies charac...

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Bibliographic Details
Main Authors: Anna Privitera, Vincenzo Cardaci, Dhanushka Weerasekara, Miriam Wissam Saab, Lidia Diolosà, Annamaria Fidilio, Renaud Blaise Jolivet, Giuseppe Lazzarino, Angela Maria Amorini, Massimo Camarda, Susan Marie Lunte, Filippo Caraci, Giuseppe Caruso
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Pharmacology
Subjects:
carnosine
human microglia
inflammation
oxidative stress
energy metabolism
depression
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1161794/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1161794/full

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