Langerhans cell histiocytosis: current advances in molecular pathogenesis

Langerhans cell histiocytosis (LCH) is a rare and clinically heterogeneous hematological disease characterized by the accumulation of mononuclear phagocytes in various tissues and organs. LCH is often characterized by activating mutations of the mitogen-activated protein kinase (MAPK) pathway with B...

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Bibliographic Details
Main Authors: Tommaso Sconocchia, Johannes Foßelteder, Giuseppe Sconocchia, Andreas Reinisch
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1275085/full