Development of a chimeric Zika vaccine using a licensed live-attenuated flavivirus vaccine as backbone
Given the recent Zika virus (ZIKV) epidemic, development of an effective vaccine is of high importance. Here, the authors use a licensed live-attenuated flavivirus vaccine backbone to develop a ZIKV vaccine and determine immunogenicity, safety and protection profiles in different animal models.
Bibliographic Details
| Main Authors: |
Xiao-Feng Li,
Hao-Long Dong,
Hong-Jiang Wang,
Xing-Yao Huang,
Ye-Feng Qiu,
Xue Ji,
Qing Ye,
Chunfeng Li,
Yang Liu,
Yong-Qiang Deng,
Tao Jiang,
Gong Cheng,
Fu-Chun Zhang,
Andrew D. Davidson,
Ya-Jun Song,
Pei-Yong Shi,
Cheng-Feng Qin |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2018-02-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-018-02975-w
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