Membrane estrogen receptor-α contributes to female protection against high-fat diet-induced metabolic disorders

Membrane estrogen receptor-α contributes to female protection against high-fat diet-induced metabolic disorders

BackgroundEstrogen Receptor α (ERα) is a significant modulator of energy balance and lipid/glucose metabolisms. Beyond the classical nuclear actions of the receptor, rapid activation of intracellular signaling pathways is mediated by a sub-fraction of ERα localized to the plasma membrane, known as M...

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Bibliographic Details
Main Authors: Aurélie Fabre, Blandine Tramunt, Alexandra Montagner, Céline Mouly, Elodie Riant, Marie-Lou Calmy, Marine Adlanmerini, Coralie Fontaine, Rémy Burcelin, Françoise Lenfant, Jean-François Arnal, Pierre Gourdy
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Endocrinology
Subjects:
sex differences
estrogen receptor alpha (ERα)
membrane-initiated steroid signaling
obesity
insulin resistance
thermogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1215947/full

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https://www.frontiersin.org/articles/10.3389/fendo.2023.1215947/full

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