Virus-like vaccines against HIV/SIV synergize with a subdominant antigen T cell vaccine
Abstract Background In non-human primates (NHPs) and humans, partial protection from HIV/SIV infection or suppression of replication is achievable by Env-binding antibodies and Gag-specific CD8+ T-cells targeting protective epitopes. Unfortunately, such T-cell responses are frequently dominated by r...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-05-01
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Series: | Journal of Translational Medicine |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12967-019-1924-1 |