Case Report: The effective treatment of patients in advanced no-small cell lung cancer patients with EGFR G719X/S768I/L861Q and acquired MET amplification: A case series and literature review

Case Report: The effective treatment of patients in advanced no-small cell lung cancer patients with EGFR G719X/S768I/L861Q and acquired MET amplification: A case series and literature review

Preclinical cases suggest that EGFR tyrosine kinase inhibitors (TKIs) plus MET TKIs are a potential therapy for non-classical EGFR mutant lung cancers with MET amplification acquired resistance. Herein, we report for the first time the effectiveness of novel combination treatment regimens for patien...

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Bibliographic Details
Main Authors: Yun Zhao, Cuiyun Su, Lina Shi, Wenqi Luo, Zhen Liu, Chuqiao Liang, Huilin Wang, Ruiling Ning, Qitao Yu, Wei Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Oncology
Subjects:
uncommon mutation
EGFR G719X/S768I/L861Q
resistance
MET amplification
non-small cell lung cancer (NSCLC)
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1126325/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1126325/full

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