Adjuvant Pam3CSk4 does not improve the immunization against Cryptococcus gattii infection in C57BL/6 mice

Adjuvant Pam3CSk4 does not improve the immunization against Cryptococcus gattii infection in C57BL/6 mice

Background Cryptococcosis is a relevant invasive fungal infection that affects immunocompromised and immunocompetent individuals when caused by Cryptococcus gattii. Host innate and adaptive immune responses can be subverted by C. gattii, that blocks the differentiation of T helper (Th) 1 and Th17 ce...

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Bibliographic Details
Main Authors: Gabriela Yamazaki de Campos, Patrícia Kellen Martins Oliveira-Brito, Júlia Garcia Guimarães, Letícia Serafim da Costa, Javier Emílio Lazo Chica, Thiago Aparecido da Silva
Format: Article
Language:English
Published: PeerJ Inc. 2023-01-01
Series:PeerJ
Subjects:
Cryptococcus gattii
TLR2
Vaccine
Pam3CSK4
Immunomodulation
Online Access:https://peerj.com/articles/14778.pdf

Internet

https://peerj.com/articles/14778.pdf

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