BTLA Expression in CLL: Epigenetic Regulation and Impact on CLL B Cell Proliferation and Ability to IL-4 Production

BTLA Expression in CLL: Epigenetic Regulation and Impact on CLL B Cell Proliferation and Ability to IL-4 Production

In our previous study, while chronic lymphocytic leukemia (CLL) cases showed higher levels of B and T lymphocyte attenuator (BTLA) mRNA compared to controls, lower BTLA protein expression was observed in cases compared to controls. Hence we hypothesize that micro RNA (miR) 155-5p regulates BTLA expr...

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Bibliographic Details
Main Authors: Lidia Karabon, Anna Andrzejczak, Lidia Ciszak, Anna Tomkiewicz, Aleksandra Szteblich, Agnieszka Bojarska-Junak, Jacek Roliński, Dariusz Wołowiec, Tomasz Wróbel, Agata Kosmaczewska
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cells
Subjects:
CLL
BTLA
IL-4
proliferation
epigenetic regulation
miR-155-5p
Online Access:https://www.mdpi.com/2073-4409/10/11/3009

Internet

https://www.mdpi.com/2073-4409/10/11/3009

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