Nimbolide Inhibits SOD2 to Control Pancreatic Ductal Adenocarcinoma Growth and Metastasis

Nimbolide Inhibits SOD2 to Control Pancreatic Ductal Adenocarcinoma Growth and Metastasis

Reactive oxygen species are frequently associated with various cancers including pancreatic ductal adenocarcinomas (PDACs). Superoxide dismutase 2 (SOD2) is an enzyme that plays an important role in reactive oxygen species (ROS) signaling. Investigating the molecular function and biological function...

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Bibliographic Details
Main Authors: Tugba Mehmetoglu-Gurbuz, Rajkumar Lakshmanaswamy, Karla Perez, Mayra Sandoval, Casandra A. Jimenez, Jackelyn Rocha, Rachel Madeline Goldfarb, Courtney Perry, Alejandra Bencomo, Nishkala Neela, Jose A. Barragan, Raquel Sanchez, Risa Mia Swain, Ramadevi Subramani
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Antioxidants
Subjects:
superoxide dismutase 2 (SOD2)
reactive oxygen species (ROS)
nimbolide
proliferation
metastasis
pancreatic cancer
Online Access:https://www.mdpi.com/2076-3921/12/10/1791

Internet

https://www.mdpi.com/2076-3921/12/10/1791

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