Modeling of cancer-related body-wide effects identifies LTB4 as a diagnostic biomarker for pancreatic cancer

Summary: Background: Cancer elicits a complex adaptive response in an organism. Limited information is available for the body-wide effects induced by cancer. Here, we evaluated multiorgan changes in mouse models of pancreatic ductal adenocarcinoma (PDAC) and its precursor lesions (pancreatic intrae...

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Bibliographic Details
Main Authors: Shu-Heng Jiang, Dejun Liu, Li-Peng Hu, Shan Zhang, Yanqiu Yu, Yong-Wei Sun, Jianguang Ji, Zhi-Gang Zhang
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:EBioMedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396422002316