Analysis of Global Collection of Group A <italic toggle="yes">Streptococcus</italic> Genomes Reveals that the Majority Encode a Trio of M and M-Like Proteins

Analysis of Global Collection of Group A <italic toggle="yes">Streptococcus</italic> Genomes Reveals that the Majority Encode a Trio of M and M-Like Proteins

ABSTRACT The core Mga (multiple gene activator) regulon of group A Streptococcus (GAS) contains genes encoding proteins involved in adhesion and immune evasion. While all GAS genomes contain genes for Mga and C5a peptidase, the intervening genes encoding M and M-like proteins vary between strains. T...

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Bibliographic Details
Main Authors: Hannah R. Frost, Mark R. Davies, Valérie Delforge, Dalila Lakhloufi, Martina Sanderson-Smith, Velusamy Srinivasan, Andrew C. Steer, Mark J. Walker, Bernard Beall, Anne Botteaux, Pierre R. Smeesters
Format: Article
Language:English
Published: American Society for Microbiology 2020-02-01
Series:mSphere
Subjects:
Streptococcus pyogenes
Mga regulon
M-like proteins
global GAS diversity
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00806-19

Internet

https://journals.asm.org/doi/10.1128/mSphere.00806-19

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