A zero inflated log-normal model for inference of sparse microbial association networks.

The advent of high-throughput metagenomic sequencing has prompted the development of efficient taxonomic profiling methods allowing to measure the presence, abundance and phylogeny of organisms in a wide range of environmental samples. Multivariate sequence-derived abundance data further has the pot...

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Bibliographic Details
Main Authors: Vincent Prost, Stéphane Gazut, Thomas Brüls
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-06-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1009089