Nicotinic Acetylcholine Receptor α7 Subunit Mediates Migration of Vascular Smooth Muscle Cells Toward Nicotine

GbaSM-4 cells, vascular smooth muscle cells (VSMCs) derived from brain basilar arteries, were shown to migrate toward d-nicotine by augmenting the actin cytoskeleton in their cell bodies and lamellipodia, and expression of nicotinic acetylcholine receptor (α7-nAChR) was detected in GbaSM-4 cells. Th...

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Bibliographic Details
Main Authors: Sheng Li, Tiejun Zhao, Hong Xin, Li-Hong Ye, Xiaodong Zhang, Hideyuki Tanaka, Akio Nakamura, Kazuhiro Kohama
Format: Article
Language:English
Published: Elsevier 2004-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319325022