Microglia-Derived Insulin-like Growth Factor 1 Is Critical for Neurodevelopment

Microglia-Derived Insulin-like Growth Factor 1 Is Critical for Neurodevelopment

Insulin-like growth factor 1 (IGF-1) is a peptide hormone essential for the proper development and growth of the organism, as a complete knockout of <i>Igf1</i> in mice is lethal, causing microcephaly, growth retardation and the defective development of organs. In the central nervous sys...

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Bibliographic Details
Main Authors: Dominika Rusin, Lejla Vahl Becirovic, Gabriela Lyszczarz, Martin Krueger, Anouk Benmamar-Badel, Cecilie Vad Mathiesen, Eydís Sigurðardóttir Schiöth, Kate Lykke Lambertsen, Agnieszka Wlodarczyk
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Cells
Subjects:
microglia
neonatal microglia
<i>Igf1</i>
neurodevelopment
neophobia
primary myelination
Online Access:https://www.mdpi.com/2073-4409/13/2/184

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https://www.mdpi.com/2073-4409/13/2/184

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