Colon cancer cells secrete exosomes to promote self-proliferation by shortening mitosis duration and activation of STAT3 in a hypoxic environment

Colon cancer cells secrete exosomes to promote self-proliferation by shortening mitosis duration and activation of STAT3 in a hypoxic environment

Abstract Colon-cancer-cell-derived exosomes (CDEs) are emerging mediators of tumorigenesis and serve as messengers of intercellular communication; however, whether the CDEs affect the proliferation of colon cancer cells themselves remains unknown. In the current study, the CDEs isolated from human c...

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Bibliographic Details
Main Authors: Ruixue Ren, Hua Sun, Cui Ma, Jiatao Liu, Hua Wang
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Cell & Bioscience
Subjects:
Exosomes
Hypoxia
Cell proliferation
Mitosis
STAT3
Online Access:http://link.springer.com/article/10.1186/s13578-019-0325-8

Internet

http://link.springer.com/article/10.1186/s13578-019-0325-8

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