Intermittent hypoxia inhibits epinephrine-induced transcriptional changes in human aortic endothelial cells

Abstract Obstructive sleep apnea (OSA) is an independent risk factor for cardiovascular disease. While intermittent hypoxia (IH) and catecholamine release play an important role in this increased risk, the mechanisms are incompletely understood. We have recently reported that IH causes endothelial c...

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Bibliographic Details
Main Authors: Rengul Cetin-Atalay, Angelo Y. Meliton, Kaitlyn A. Sun, Mariel E. Glass, Parker S. Woods, Ying-Jie Peng, Yun Fang, Robert B. Hamanaka, Nanduri R. Prabhakar, Gökhan M. Mutlu
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-21614-5