Timosaponin Inhibit Proliferation and Stem Cell Formation of Lung Cancer Through Regulating Hedgehog Signaling-mediated SOX2

Timosaponin Inhibit Proliferation and Stem Cell Formation of Lung Cancer Through Regulating Hedgehog Signaling-mediated SOX2

Objective To explore the effects of Timosaponin (TMS) on lung cancer and cancer stem cell (CSC) and its underlying mechanism. Methods MTS, Hoechst 33342 staining, flow cytometry, cell migration and plate cloning experiments were used to detect the effect of TMS on cell biological functions. The effe...

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Bibliographic Details
Main Authors: CAO Song, YAN Xiaoyan, MA Jun, JING Wenjiang, ZHANG Shulian, WANG Juanyi, LI Xiang, WU Xiang
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2020-08-01
Series:Zhongliu Fangzhi Yanjiu
Subjects:
lung cancer
stem cells
timosaponin
hedgehog signaling pathway
sox2
Online Access:http://html.rhhz.net/ZLFZYJ/html/8578.2020.20.0109.htm

Internet

http://html.rhhz.net/ZLFZYJ/html/8578.2020.20.0109.htm

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