Inferring transcriptional and microRNA‐mediated regulatory programs in glioblastoma

Inferring transcriptional and microRNA‐mediated regulatory programs in glioblastoma

Abstract Large‐scale cancer genomics projects are profiling hundreds of tumors at multiple molecular layers, including copy number, mRNA and miRNA expression, but the mechanistic relationships between these layers are often excluded from computational models. We developed a supervised learning frame...

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Bibliographic Details
Main Authors: Manu Setty, Karim Helmy, Aly A Khan, Joachim Silber, Aaron Arvey, Frank Neezen, Phaedra Agius, Jason T Huse, Eric C Holland, Christina S Leslie
Format: Article
Language:English
Published: Springer Nature 2012-08-01
Series:Molecular Systems Biology
Subjects:
gene regulatory programs
integrative cancer genomics
microRNA regulation
microRNAs in glioblastoma
Online Access:https://doi.org/10.1038/msb.2012.37

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https://doi.org/10.1038/msb.2012.37

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