Asymmetric expression of H19 and ADIPOQ in concave/convex paravertebral muscles is associated with severe adolescent idiopathic scoliosis

Abstract Background Adolescent idiopathic scoliosis (AIS) is the most common paediatric spinal deformity. The etiology and pathology of AIS remain unexplained, and have been reported to involve a combination of genetic and epigenetic factors. Since paravertebral muscle imbalance plays an important r...

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Bibliographic Details
Main Authors: Heng Jiang, Fu Yang, Tao Lin, Wei Shao, Yichen Meng, Jun Ma, Ce Wang, Rui Gao, Xuhui Zhou
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Molecular Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s10020-018-0049-y