The Kinesin-12 Kif15 is a processive track-switching tetramer
Kinesin-12 motors are a little studied branch of the kinesin superfamily with the human protein (Kif15) implicated in spindle mechanics and chromosome movement. In this study, we reconstitute full-length hKif15 and its microtubule-targeting factor hTpx2 in vitro to gain insight into the motors mode...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2014-03-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/01724 |