The Kinesin-12 Kif15 is a processive track-switching tetramer

The Kinesin-12 Kif15 is a processive track-switching tetramer

Kinesin-12 motors are a little studied branch of the kinesin superfamily with the human protein (Kif15) implicated in spindle mechanics and chromosome movement. In this study, we reconstitute full-length hKif15 and its microtubule-targeting factor hTpx2 in vitro to gain insight into the motors mode...

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Bibliographic Details
Main Authors: Hauke Drechsler, Toni McHugh, Martin R Singleton, Nicholas J Carter, Andrew D McAinsh
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-03-01
Series:eLife
Subjects:
kinesin-12
mitotic spindle
mitosis
Online Access:https://elifesciences.org/articles/01724

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