Synthesis and Antitumor Activity of Doxycycline Polymeric Nanoparticles: Effect on Tumor Apoptosis in Solid Ehrlich Carcinoma

Synthesis and Antitumor Activity of Doxycycline Polymeric Nanoparticles: Effect on Tumor Apoptosis in Solid Ehrlich Carcinoma

Objectives: The aim of this study was to prepare doxycycline polymeric nanoparticles (DOXY-PNPs) with hope to enhance its chemotherapeutic potential against solid Ehrlich carcinoma (SEC). Methods: Three DOXY-PNPs were formulated by nanoprecipitation method using hydroxypropyl methyl cellulose (HPMC)...

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Bibliographic Details
Main Authors: Ahmed R. Gardouh, Mohammed A. Attia, Eman T. Enan, Alaaeldeen M. Elbahaie, Rania A. Fouad, Mohamed El-Shafey, Amal M. Youssef, Suliman Y. Alomar, Zinab Abd-Elhady Ali, Sawsan A. Zaitone, Mona K.E. Qushawy
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Molecules
Subjects:
apoptosis
doxycycline
solid Ehrlich carcinoma
female mice
hydroxypropyl methyl cellulose (HPMC), polymeric nanoparticles
Online Access:https://www.mdpi.com/1420-3049/25/14/3230

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https://www.mdpi.com/1420-3049/25/14/3230

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