Usp18 driven enforced viral replication in dendritic cells contributes to break of immunological tolerance in autoimmune diabetes.

Usp18 driven enforced viral replication in dendritic cells contributes to break of immunological tolerance in autoimmune diabetes.

Infection with viruses carrying cross-reactive antigens is associated with break of immunological tolerance and induction of autoimmune disease. Dendritic cells play an important role in this process. However, it remains unclear why autoimmune-tolerance is broken during virus infection, but usually...

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Bibliographic Details
Main Authors: Nadine Honke, Namir Shaabani, Dong-Er Zhang, George Iliakis, Haifeng C Xu, Dieter Häussinger, Mike Recher, Max Löhning, Philipp A Lang, Karl S Lang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3812017?pdf=render

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http://europepmc.org/articles/PMC3812017?pdf=render

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