CD90 Marks a Mesenchymal Program in Human Thymic Epithelial Cells In Vitro and In Vivo

CD90 Marks a Mesenchymal Program in Human Thymic Epithelial Cells In Vitro and In Vivo

Thymic epithelium is critical for the structural integrity of the thymus and for T cell development. Within the fully formed thymus, large numbers of hematopoietic cells shape the thymic epithelium into a scaffold-like structure which bears little similarity to classical epithelial layers, such as t...

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Bibliographic Details
Main Authors: Shicheng Sun, Jacky Y. Li, Hieu T. Nim, Adam Piers, Mirana Ramialison, Enzo R. Porrello, Igor E. Konstantinov, Andrew G. Elefanty, Edouard G. Stanley
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Immunology
Subjects:
human thymic epithelial cells
epithelial and mesenchymal components
primary cells culture
pluripotent stem cell differentiation
CD90/Thy1
cell identity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.846281/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.846281/full

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