Inhibitory activities of short linear motifs underlie Hox interactome specificity in vivo

Hox proteins are well-established developmental regulators that coordinate cell fate and morphogenesis throughout embryogenesis. In contrast, our knowledge of their specific molecular modes of action is limited to the interaction with few cofactors. Here, we show that Hox proteins are able to intera...

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Bibliographic Details
Main Authors: Manon Baëza, Séverine Viala, Marjorie Heim, Amélie Dard, Bruno Hudry, Marilyne Duffraisse, Ana Rogulja-Ortmann, Christine Brun, Samir Merabet
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-04-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/06034