The Central Spike Complex of Bacteriophage T4 Contacts PpiD in the Periplasm of <i>Escherichia coli</i>

Infecting bacteriophage T4 uses a contractile tail structure to breach the envelope of the <i>Escherichia coli</i> host cell. During contraction, the tail tube headed with the “central spike complex” is thought to mechanically puncture the outer membrane. We show here that a purified tip...

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Bibliographic Details
Main Authors: Sabrina Wenzel, Mikhail M. Shneider, Petr G. Leiman, Andreas Kuhn, Dorothee Kiefer
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/12/10/1135