IL-33 Induces an Antiviral Signature in Mast Cells but Enhances Their Permissiveness for Human Rhinovirus Infection

Mast cells (MCs) are classically associated with allergic asthma but their role in antiviral immunity is unclear. Human rhinoviruses (HRVs) are a major cause of asthma exacerbations and can infect and replicate within MCs. The primary site of HRV infection is the airway epithelium and MCs localise t...

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Bibliographic Details
Main Authors: Charlene Akoto, Anna Willis, Chiara F. Banas, Joseph A. Bell, Dean Bryant, Cornelia Blume, Donna E. Davies, Emily J. Swindle
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/14/11/2430