Acetaminophen changes the RNA m6A levels and m6A-related proteins expression in IL-1β-treated chondrocyte cells

Acetaminophen changes the RNA m6A levels and m6A-related proteins expression in IL-1β-treated chondrocyte cells

Abstract Background Acetaminophen is commonly recommended for the early analgesia of osteoarthritis. However, the molecular mechanism by which it acts remains unknown. The aim of this study is to investigate the effect of acetaminophen on inflammation and extracellular matrix degradation in human ch...

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Bibliographic Details
Main Authors: Jie Gao, Yan Li, Zijin Liu, Dong Wang, Huawu Zhang
Format: Article
Language:English
Published: BMC 2022-10-01
Series:BMC Molecular and Cell Biology
Subjects:
Acetaminophen
Chondrocyte cell
Interleukin-1β
RNA N6-methyladenosine modification
ALKBH5
Inflammatory factors
Online Access:https://doi.org/10.1186/s12860-022-00444-3

Internet

https://doi.org/10.1186/s12860-022-00444-3

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