A Novel Mitochondrial Targeted Compound Phosundoxin Showing Potent Antifungal Activity against Common Clinical Pathogenic Fungi

The current increase in resistance to antifungal drugs indicates that there is an urgent need to explore novel antifungal drugs with different mechanisms of action. Phosundoxin is a biphenyl aliphatic amide using a TPP-targeting strategy which targets mitochondria. To provide insights into the antif...

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Bibliographic Details
Main Authors: Shu Zhang, Yuanyuan Geng, Bin Wei, Yangzhen Lu, Lihua He, Fei Zhao, Jianzhong Zhang, Zhaohai Qin, Jie Gong
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Journal of Fungi
Subjects:
Online Access:https://www.mdpi.com/2309-608X/10/1/28