Recent advances in polymeric microparticle-based drug delivery systems for knee osteoarthritis treatment

Due to the poor bioavailability and high joint clearance of drugs, sustained delivery of therapeutic agents has proven difficult in the treatment of osteoarthritis (OA). Intra-articular (IA) drug delivery strategy is an attractive option for enhancing OA patients’ prognosis, for which various polyme...

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Bibliographic Details
Main Authors: Guangxin Wang, Xin-an Zhang, Leonid Kapilevich, Mingjie Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1290870/full