Shared epitope alleles remain a risk factor for anti-citrullinated proteins antibody (ACPA)--positive rheumatoid arthritis in three Asian ethnic groups.

BACKGROUND: To investigate the associations between HLA-DRB1 shared epitope (SE) alleles and rheumatoid arthritis in subsets of rheumatoid arthritis defined by autoantibodies in three Asian populations from Malaysia. METHODS: 1,079 rheumatoid arthritis patients and 1,470 healthy controls were includ...

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Bibliographic Details
Main Authors: Too Chun-Lai, Leonid Padyukov, Jasbir Singh Dhaliwal, Emeli Lundström, Abqariyah Yahya, Nor Asiah Muhamad, Lars Klareskog, Lars Alfredsson, Per Tobias Larsson, Shahnaz Murad, Malaysian Epidemiological Investigation of Rheumatoid Arthritis (MyEIRA) Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3115981?pdf=render