The emerging roles of CDK12 in tumorigenesis
Abstract Cyclin-dependent kinases (CDKs) are key regulators of both cell cycle progression and transcription. Since dysregulation of CDKs is a frequently occurring event driving tumorigenesis, CDKs have been tested extensively as targets for cancer therapy. Cyclin-dependent kinase 12 (CDK12) is a tr...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2017-10-01
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| Series: | Cell Division |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13008-017-0033-x |