The relevance of cerebrospinal fluid α-synuclein levels to sporadic and familial Alzheimer’s disease

The relevance of cerebrospinal fluid α-synuclein levels to sporadic and familial Alzheimer’s disease

Abstract Accumulating evidence demonstrating higher cerebrospinal fluid (CSF) α-synuclein (αSyn) levels and αSyn pathology in the brains of Alzheimer’s disease (AD) patients suggests that αSyn is involved in the pathophysiology of AD. To investigate whether αSyn could be related to specific aspects...

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Bibliographic Details
Main Authors: Daniel Twohig, Elena Rodriguez-Vieitez, Sigrid B. Sando, Guro Berge, Camilla Lauridsen, Ina Møller, Gøril R. Grøntvedt, Geir Bråthen, Kalicharan Patra, Guojun Bu, Tammie L. S. Benzinger, Celeste M. Karch, Anne Fagan, John C. Morris, Randall J. Bateman, Agneta Nordberg, Linda R. White, Henrietta M. Nielsen, for the Dominantly Inherited Alzheimer Network (DIAN)
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Acta Neuropathologica Communications
Subjects:
Alzheimer’s disease
Mild cognitive impairment
alpha-synuclein
Biomarkers
APOEε4
Online Access:http://link.springer.com/article/10.1186/s40478-018-0624-z

Internet

http://link.springer.com/article/10.1186/s40478-018-0624-z

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