Characterization of glioblastoma spheroid models for drug screening and phototherapy assays

Characterization of glioblastoma spheroid models for drug screening and phototherapy assays

Glioblastoma (GBM) spheroids present as a promising alternative testing platform for in vivo models of brain cancer, aiming at the 3Rs principle of animal use in pre-clinical trials. However, the poor characterization and irreproducibility of various GBM-based spheroids have hampered the achievement...

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Bibliographic Details
Main Authors: Samara Rodrigues Alves, Italo Rodrigo Calori, Hong Bi, Antonio Claudio Tedesco
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:OpenNano
Subjects:
Glioblastoma
Multicellular tumor spheroid
3D cell model
Nanoparticles
Photodynamic therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2352952022000780

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http://www.sciencedirect.com/science/article/pii/S2352952022000780

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