Metformin reduces the cellular DNA repair capacity and enhances the effect of curcumin on the induction of apoptosis in AGS gastric cancer cells
Abstract Background Cancer results from the accumulation of mutations in critical genes, such as DNA repair genes. But these genes are a double-edged sword, because the basis of current cancer treatment is DNA damage from chemotherapy and radiation, and the repair system can slow the healing process...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
SpringerOpen
2023-10-01
|
Series: | Egyptian Journal of Medical Human Genetics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s43042-023-00445-7 |