Immunity against Ixodes scapularis salivary proteins expressed within 24 hours of attachment thwarts tick feeding and impairs Borrelia transmission.

Immunity against Ixodes scapularis salivary proteins expressed within 24 hours of attachment thwarts tick feeding and impairs Borrelia transmission.

In North America, the black-legged tick, Ixodes scapularis, an obligate haematophagus arthropod, is a vector of several human pathogens including Borrelia burgdorferi, the Lyme disease agent. In this report, we show that the tick salivary gland transcriptome and proteome is dynamic and changes durin...

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Bibliographic Details
Main Authors: Sukanya Narasimhan, Kathleen Deponte, Nancy Marcantonio, Xianping Liang, Thomas E Royce, Kenneth F Nelson, Carmen J Booth, Benjamin Koski, John F Anderson, Fred Kantor, Erol Fikrig
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-05-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1866177?pdf=render

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http://europepmc.org/articles/PMC1866177?pdf=render

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